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Melanoma Skin Cancer Side Effect Associated With Erectile Dysfunction (ED) Drugs Cialis, Levitra, Viagra, Staxyn, And Stendra, As Well As PAH Medications Revatio And Adcirca

 
According to an April 2014 medical journal article, Viagra (sildenafil), the most popular and well-known drug prescribed for male erectile dysfunction (ED), appears to increase the risk for malignant melanoma — but not other skin cancers like cutaneous squamous cell carcinomas nor basal cell carcinomas.

The four other brand name ED drugs that are phosphodiesterase 5 (PDE5) inhibitors, Cialis (tadalafil), Levitra (vardenafil), Staxyn (vardenafil), and Stendra (avanafil) are probably associated with an increased risk of melanoma skin cancer, too.

Cialis is also prescribed sometimes when doctors see the signs and symptoms of benign prostatic hyperplasia (BPH).

Two other phosphodiesterase 5 (PDE5) inhibitors are Revatio (sildenafil) and Adcirca (tadalafil).  These drugs are prescribed for the treatment of pulmonary arterial hypertension (PAH).

Essentially, the active ingredients sildenafil, tadalifil, vardenafil, and avanafil which are found in these ED, BPH, and PAH drugs act by inhibiting the phosphodiesterase 5 (PDE5). Experimental in vitro studies show that PDE5 inhibition augments tumor cell invasiveness.  In turn, this effect seems related to an apparent melanoma skin cancer side effect for all of the brand name drugs with these active ingredients:

  1. Sildenafil: Viagra and Revatio
  2. Tadalafil: Cialis and Adcirca
  3. Vardenafil: Levitra and Staxyn
  4. Avanafil: Stendra

The recent medical study finding which indicates an association between each of these PDE5 inhibitor drugs with invasive melanoma skin cancer might be of particular concern to patients that have used any of these drugs and who may be at an elevated risk of melanoma due to a history of:

  • extensive sun exposure;
  • basal or squamous cell skin cancers;
  • Parkinson disease (which causes autonomic erectile dysfunction and is associated with elevated risk of melanoma); or,
  • other family members diagnosed with melanoma.

We are currently investigating cases of melanoma in men who used Viagra, Cialis, Levitra, Staxyn, or Stendra as well as men and women who used Revatio or Adcirca, as possible drug injury lawsuits against the responsible pharmaceutical companies.  For example:

Viagra / Cialis – Melanomas (3 sites) – 35 yr old man
Cialis – Melanoma – 68 yr old man
Cialis / Viagra – Melanoma – 81 yr old man
Cialis – Melanoma Skin Cancer – 56 yr old man
Viagra – Melanoma Carcinoma – 46 yr old man
Cialis / Viagra – Melanoma Skin Cancer – 47 yr old man
Levitra – Melanoma – 69 yr old man
Viagra / Cialis – Malignant Melanoma – 69 yr old man
Viagra / Cialis – Melanoma, Stage 3 – 67 yr old man
Viagra / Cialis – Melanoma – 77 yr old man

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Free Case Evaluation: Viagra / Cialis / Levitra / Staxyn / Stendra / Revatio / Adcirca

We encourage you to submit a Drug Injury Law Case Review – it is free, confidential, and there is no obligation.  Or, if you prefer, call our toll-free number, (800) 426-9535, to speak directly to attorney Tom Lamb about a possible drug injury case.  Either way, you will get Mr. Lamb’s impressions — not an intake person, a paralegal, nor some other lawyer — about your case based on his many years of experience.

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Viagra – Melanoma MDL Might Include Cialis Lawsuits And Levitra Cases

As regards drug injury lawsuits concerning the melanoma side effect of male erectile dysfunction (ED) pills, that litigation began with Viagra cases being filed against Pfizer, the drug company responsible for Viagra. By April 2016 there was a sufficient federal court Viagra lawsuits filed that the Judicial Panel on Multidistrict Litigation (JPML) decided to create the so-called Viagra MDL, known fully as IN RE: VIAGRA (SILDENAFIL CITRATE) PRODUCTS LIABILITY LITIGATION — MDL No. 2691. This federal court consolidation of Viagra lawsuits was assigned to Judge Richard Seeborg, of the Northern District of California. To date, more than 200 Viagra cases are pending before Judge Seeborg in San Francisco related to individuals being diagnosed with melanoma after using Viagra.

Not unexpectedly, the filing of Viagra lawsuits has been followed by the filing of Cialis lawsuits on behalf of men who have developed malignant melanoma, some of whom have died, unfortunately.

In September 2016 the plaintiffs in some of those federal court Cialis cases asked the JPML to add their lawsuits to the Viagra MDL for various reasons, including the need for judicial economy, consistency in rulings, and the commonality among the Viagra and Cialis melanoma claims. That motion for what would then be a Viagra – Cialis MDL is currently pending.

Next, it is likely that there will be Levitra – melanoma lawsuits filed in the next few months. And, further, once the number of Levitra cases filed in federal court reaches a certain level, one anticipates a motion filed with the JPML requesting that those melanoma cases get added to an expanded federal court Viagra MDL.

We are currently investigating cases of melanoma in men who used Viagra, Cialis, and/or Levitra. These cases are possible drug injury lawsuits against the responsible pharmaceutical companies, not the prescribing doctors.

[Read this article in full at original source]

Earlier articles by attorney Tom Lamb on the Side Effects Blog:

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Viagra / Cialis / Levitra / Staxyn / Stendra / Revatio / Adcirca Drug Injury or Death Case Evaluation

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All content by attorney Tom Lamb

Law Offices of Thomas J. Lamb, P.A.
1908 Eastwood Road, Suite 225
Wilmington, NC 28403
(800) 426-9535
ThomasJLamb@DrugInjuryLaw.com
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