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These Proton Pump Inhibitors (PPIs) Can Cause Side Effects Such As Acute Interstitial Nephritis, Chronic Kidney Disease, And Acute Renal Injury
There is growing body of medical evidence which indicates that some popular heartburn drugs and acid reflux medicines like Prevacid, Prilosec, and Nexium can cause some serious kidney-related side effects.
It is important to know these side effects can be caused by any of the proton pump inhibitors (PPIs) heartburn drugs and acid reflux medicines, not just the three listed above. And we point out they can be caused by pills that are bought over-the-counter (without a prescription) as well as those pills obtained at a pharmacy when filling a doctor’s prescription.
In more detail, the use of these proton pump inhibitors (PPIs) for as little as a couple of weeks time can result in an increased risk of developing:
- Acute Interstitial Nephritis (AIN)
- Chronic Kidney Disease (CKD)
- End-Stage Renal Disease (ESRD)
- Severe Renal Impairment
- Kidney / Renal Failure
- Acute Kidney Injury
Further, a recent medical study shows that the longer the period of use of pills like Prevacid, Prilosec, and Nexium, the greater the risk of developing these serious kidney or renal conditions.
These acid reflux and heart burn medications are available by prescription and over-the-counter (OTC) from various pharmaceutical companies. For example:
NEXIUM | prescription drug | AstraZeneca LP
NEXIUM 24HR | over-the-counter | Pfizer Consumer Healthcare
PRILOSEC | prescription drug | AstraZeneca LP
PRILOSEC OTC | over-the-counter | Procter & Gamble Manufacturing Co.
PREVACID | prescription drug | Takeda Pharmaceuticals America, Inc.
PREVACID 24 HR | over-the-counter | Novartis Consumer Health, Inc.
We are currently investigating possible drug injury lawsuits against the responsible pharmaceutical companies for people who have developed any of the kidney-related medical problems listed above. These lawsuits are not limited to Nexium, Prilosec, and Prevacid.
Rather, the lawsuits can be based on using any of the brand name proton pump inhibitors (PPIs) heartburn drugs and acid reflux medicines. And these cases involve such pills that were obtained by prescription and/or over-the-counter.
Here are a few cases we currently have under investigation:
- Prilosec / Prevacid / Nexium – Kidney Disease, Stage 3 – 74 yrs old
- Nexium – Chronic Kidney Disease (CKD); Death – 78 yr old woman
- Prilosec – Acute Interstitial Nephritis / PPI-induced AIN – 86 yr old man
- Nexium / Prevacid – Kidney Disease, Stage 2 – 66 yr old woman
- Prilosec – Kidney / Renal Failure (sudden onset) – 42 yr old man
- Prilosec – Chronic Kidney Disease; Kidney Failure – 51 yr old woman
- Nexium / Prilosec – Renal Failure; Kidney Transplant – 52 yr old woman
- Prevacid – Kidney / Renal Failure – 67 yr old woman
- Prevacid / Prilosec – Kidney / Renal Failure – 48 yr old man
- Nexium / Prevacid – Kidney / Renal Failure – 56 yr old man
We encourage you to submit a Drug Injury Law Case Review – it is free, confidential, and there is no obligation. Or, if you prefer, call our toll-free number, (800) 426-9535, to speak directly to attorney Tom Lamb about a possible drug injury case. Either way, you will get Mr. Lamb’s impressions — not an intake person, a paralegal, nor some other lawyer — about your case based on his many years of experience.
In August 2017 the United States Judicial Panel on Multidistrict Litigation (JPML) granted a second motion for centralization or consolidation of federal court lawsuits brought by plaintiffs in proton-pump inhibitors (PPIs) cases alleging kidney injury.
In more detail, the JPML established IN RE: PROTON-PUMP INHIBITOR PRODUCTS LIABILITY LITIGATION (NO. II) – MDL No. 2789. From the JPML’s Transfer Order filed on August 2, 2017 we get these details:
In the complaints in these 161 personal injury and wrongful death actions, plaintiffs allege that as a result of taking one or more proton-pump inhibitors (PPIs), they or their decedents suffered kidney injury (e.g., chronic kidney disease (CKD), acute interstitial nephritis, end stage renal disease, or kidney failure). Plaintiffs allege that defendants failed to adequately warn of the negative effects and risks associated with PPIs….
Notably, during this second time around only one drug company, Takeda. was still opposed to the creation of any PPIs federal court MDL. But the JPML was not convinced by Takeda’s various arguments in opposition, as seen from this excerpt from the Transfer Order:
And, although it is true that AstraZeneca is sued in far more actions than Takeda, a significant number of actions are “mixed use” cases in which the plaintiffs allege use of more than one PPI, and sue Takeda and one or more other PPI manufacturers, including AstraZeneca. The prospect of additional cases against Takeda does not seem far-fetched . Given these circumstances, including the seemingly indivisible nature of plaintiffs’ alleged injuries in the “mixed use” cases, we decline to carve out from the MDL cases or claims against Takeda. [footnotes omitted]
Lastly, this point – which may have been a factor for the JPML when ruling this time on the Prilosec / Prevacid / Nexium federal court MDL consolidation – was mentioned in a footnote for the August 2017 Transfer Order: “The variety of alleged kidney injuries arguably has diminished, as most plaintiffs allege that they suffer from [chronic kidney disease (CKD)]….”
We continue to monitor legal and medical developments regarding the drug injury aspects of Nexium, Prevacid, and Prilosec.
- Prevacid, Nexium, And Prilosec Linked To Risk Of Chronic Kidney Damage
- Long-Term Use Of Prevacid, Prilosec, and Nexium May Lead To Strokes
- How Long-Term Use Of Heartburn Drug Nexium Might Cause Kidney Problems
- Acute Interstitial Nephritis: A Side Effect of Nexium, Prevacid, Etc.
- Heartburn Medication Nexium Might Cause Kidney-Related Side Effects
All content by attorney Tom Lamb