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New-Onset Diabetes Mellitus (DM) Or Type-2 Diabetes Associated With Lipitor And Other Statins
Statins are a class of prescription drugs used together with diet and exercise to reduce blood levels of low-density lipoprotein (LDL) cholesterol (“bad cholesterol”). One of these medications is Lipitor (atorvastatin) from Pfizer.
From the February 28, 2012 “FDA Drug Safety Communication: Important safety label changes to cholesterol-lowering statin drug”:
… A recent study by Culver et al., using data from the Women’s Health Initiative, reported that statin use conveys an increased risk of new-onset diabetes in postmenopausal women, and noted that the effect appears to be a medication class effect, unrelated to potency or to individual statin.
Based on clinical trial meta-analyses and epidemiological data from the published literature, information concerning an effect of statins on incident diabetes and increases in HbA1c and/or fasting plasma glucose was added to statin labels. [footnotes omitted]
And from a January 2012 medical journal article, Statin use and risk of diabetes mellitus in postmenopausal women in the Women’s Health Initiative: “However, the consequences of statin-induced DM have not been specifically defined and deserve more attention.” [emphasis added]
We will continue to watch for medical and regulatory developments as regards new-onset diabetes mellitus (DM), or Type-2 diabetes, associated with Lipitor and other statins.
Earlier articles by attorney Tom Lamb on the Side Effects Blog:
- Pfizer’s Lipitor Statin Drug For Treatment Of High Cholesterol Linked To An Increased Risk Of Type-2 Diabetes In Some Older And Post-Menopausal Women
All content by attorney Tom Lamb